Redox regulation in Life
Day 1 | Monday, 31 March 2025
14:30-16:30 Arrival and Registration (Campus Saarbrücken, Building B 2.1)
16:30-16:45 Welcome by Bruce & Kathrin
16:45-17:30 Opening talk: Ursula Jakob
From development to aging: The role of redox sensitive histone modifiers
18:00 Get-together at AC Saarbrücken (on Campus, Building A 3.2)
Day 2 | Tuesday, 1 April 2025
8:30-9:00 Arrival and Registration (Campus Saarbrücken, Building B 2.1)
Session 1 Redox regulation of metabolic networks
9:00-9:30 Soni Deshwal: Mapping metabolic pathways in Coenzyme Q distribution using genome-wide
CRISPR Screening
9:30-9:50 Ana Maria Vergel Leon: Compartmentalized ROS dynamics and redox regulation in cardiomyocytes: Insights
into heart failure mechanisms
9:50-10:10 Dylan Stobbe: Oxidation by ALR stabilizes CPOX in the mitochondrial IMS to facilitate heme biosynthesis in
higher eukaryotes
10:10-10:30 Vera Skafar: Metabolic networks supporting FSP1 function and their relevance in ferroptosis cell death
10:30-11:00 Tea time/ Coffee break (in A 4.3)
Session 2 Redox signaling and cellular responses
11:00-11:30 Tobias Dansen: Dissecting cellular responses to localized redox perturbations
11:30-11:50 Carlotta Peselj: Intramitochondrial ROS-damage is detected by mitochondrial surveillance and activates
the UPRmt
11:50-12:10 Ivan Bogeski: Peroxidasin determines melanoma aggressiveness by regulating NK Cell-mediated cytotoxicity
12:10-12:30 Shayan Motiei: Redox-regulated chaperones in organismal proteostasis regulation and aging
12:30-14:00 Lunch break (in A 4.3)
Session 3 Conserved redox systems
14:00-14:30 Uladzimir Barayeu: Evolutionarily conserved cyclo-octasulfur prevents ferroptosis in mammals
14:30-15:00 Sofie Rahuel-Clermont: Enzymology of peroxiredoxin redox modification by sulfinylation
15:00-15:30 Marcel Deponte: H2S is a potential universal reducing agent for Prx6-type peroxiredoxins
15:30-16:00 Tea time/ Coffee break (in A 4.3)
Session 4 Redox on the rise
16:00-16:30 Lisa Knoke: Glutathione beyond the cytosol - Comprehensive elucidation of glutathione import
and it's role in the periplasm of Escherichia coli
16:30-17:00 Jan-Ole Niemeier: NADP redox dynamics in living plants revealed by NAPstars biosensors
17:00-17:30 Poster Pitches
17:30-19:00 Poster presentations (in A 4.3)
Day 3 | Wednesday, 2 April 2025
Session 5 Compartmentalized redox systems
9:00-9:30 Carsten Berndt: Mitochondrial oxidoreductases: FeS cluster biosynthesis and thiol-redox regulation
9:30-9:50 Irene Vercellino: Cryo-EM reveals the compositional diversity of mammalian respirasomes
9:50-10:10 Laura de Cubas: The glutathione system maintains the thiol redox balance in the mitochondria, but not in the
cytosol, of fission yeast
10:10-10:30 Johannes Herrmann: Identification of a novel oxidoreductase in the mitochondrial intermembrane space
10:30-11:00 Tea time/ Coffee break
Session 6 Dynamic of redox switches
11:00-11:30 Kai Tittmann: Lysine-cysteine redox switches - An update
11:30-11:50 Lena Kühn: Establishing a quantitative chemoproteomic labeling method for protein N chloramines
11:50-12:10 Daniela Döben: NADP redox regulation in plant immunity signalling
12:10-12:30 Danny Schilling: Exploring the regulation and function of protein persulfidation with a new quantitative assay
12:30 Closing Remarks and Farewell